'Desperate Housewives' Returns with Adultery, a New Bride & Untold Secrets!

Juicy secrets, big laughs and mysterious new neighbors loom large on the sixth-season premiere of Desperate Housewives.' Click the video for a clip!

On the premiere episode, Mike Delfino's (James Denton) bride will finally be revealed -- but will it be Katherine (Dana Delany), or maybe Susan (Teri Hatcher)? Then, Lynette (Felicity Huffman) confronts the reality of another pregnancy, and Bree (Marcia Cross) strives to free herself from Orson (Kyle MacLachlan) and her inhibitions.

Plus, Gaby (Eva Longoria Parker) contends with Carlos' (Ricardo Chavira) teenaged niece, who's now in their care. And a new family (Drea de Matteo and Jeffrey Nordling) with a dark past moves to Wisteria Lane!